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Multiple Myeloma

Authors
Mary Argent-Katwala, Ph.D.
Mary Fletcher-Louis, M.A., M.P.H.
Mariama Koroma
Lulit Solomon, M.Phil., Ph.D.
Pharmacor -- June 2005

  You Need to Know

How will the approval of bortezomib as a second-line therapy affect its sales and the sales of other agents? Thalidomide-derived immunomodulatory drugs (IMiDs) will take significant market share from thalidomide—what other drug classes stand to lose? Will stem-cell transplantation become more or less important in the next five years?

  Introduction

Multiple myeloma (MM) is an incurable hematologic cancer associated with extremely high morbidity and mortality; curative therapy is the greatest unmet need. Our research reveals that advances in the understanding of MM

  Key Findings

In 2004, incident cases of MM totaled more than 30,000; the incident population will grow modestly during our forecast period due to the aging of the population in all countries under study. Sales growth will be robust, owing to the launch of emerging agents and the use of more aggressive combinations of established and novel drugs.

Curative therapy is the greatest unmet need in the treatment of MM. Most patients die within three years of diagnosis.

Immunomodulatory agents will take significant market share as existing and emerging agents of this class steal share from older therapies that offer only disappointing survival gains.

  Why Buy This Report?

Discover how the wealth of new discoveries in the pathophysiology of MM is affecting R&D programs--how long until the next generation of targeted agents launches.

Explore striking regional differences in MM prescribing habits.

Uncover the shifting attitudes toward therapy for asymptomatic MM.

Understand how cost constraints influence the use of key drug classes.

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