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Metabolic Syndrome in the United States: Current Medical Practice and Market Opportunities

Authors
Carol D. Gleeson, M.S.
Carilee Berg, Ph.D.
PhysicianForum -- August 2004

  In This Issue...

Metabolic Syndrome is a constellation of abnormalities that includes obesity, type 2 diabetes, hypertension, and dyslipidemia. Advances in scientific knowledge, alarming increases in the prevalence of obesity, and the association with cardiovascular disease are fueling interest in the metabolic syndrome. The burgeoning market offers immense commercial opportunity, given that the combined U.S. markets for dyslipidemia, hypertension, type 2 diabetes, and obesity total more than $30 billion. However, many challenges--in scientific research, drug development, and health care--remain before this market's potential can be realized.

Decision Resources' Physician Forum survey, "Metabolic Syndrome: Current Medical Practice and Market Opportunities," explores several factors that are setting the stage for the evolution of the metabolic syndrome market in the United States: screening and diagnostic practices, current treatment, reimbursement issues, and the potential impact of fixed-dose combination agents.

This study describes the following attitudes and trends in the potential market for metabolic syndrome:

- Physician and managed care views on metabolic syndrome as a disease.

- Current screening practices for metabolic syndrome and associated disorders.

- Physician estimates of the diagnosis rate for metabolic syndrome.

- Current pharmacological approaches to treatment of metabolic syndrome.

- Use of current pharmacological therapies in patients with borderline metabolic and cardiovascular conditions associated with metabolic syndrome.

- Factors that will affect the uptake of fixed-dose combination agents, such as Pfizer's Caduet, for treatment of metabolic syndrome.

- Physician and managed care expectations of efficacy and clinical end points for drugs in development for metabolic syndrome.

The potential reimbursement climate for metabolic syndrome.

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